ESR 2: Protein structure representation

Protein structure representation

Project: Improving the in-silico structure representation of proteins

In this project the student will, in conjunction with sequence-based approaches, work to improve the representation of protein structures so that they are more informative for use in computational approaches. In RNAct this is particularly important, as we want to have the best possible three-dimensional representation of the RRM in order perform in-silico RNA docking.

This project involves a three-month secondment at the HMGU (Munich, Germany) to learn about experimental structural biology, and a one-month secondment at Giotto (Firenze, Italy) to gain insights in NMR data used in protein structure calculations.

Funding

H2020-MSCA-ITN-2018 813239 (Jan. 1, 19-Dec. 31, 23)
RNAct - Enabling proteins with RNA recognition motifs for synthetic biology and bio-analytics